Author's response to reviews Title: Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma Authors:
نویسندگان
چکیده
Min-Han Tan ([email protected]) Chin Fong Wong ([email protected]) Hwei Ling Tan ([email protected]) Ximing J Yang ([email protected]) Jonathon Ditlev ([email protected]) Daisuke Matsuda ([email protected]) Sok Kean Khoo ([email protected]) Jun Sugimura ([email protected]) Tomoaki Fujioka ([email protected]) Kyle A Furge ([email protected]) Eric Kort ([email protected]) Sophie Giraud ([email protected]) Sophie Ferlicot ([email protected]) Philippe Vielh ([email protected]) Delphine Amsellem-Ouazana ([email protected]) Bernard Debré ([email protected]) Thierry Flam ([email protected]) Nicolas Thiounn ([email protected]) Marc Zerbib ([email protected]) Gérard Benoît ([email protected]) Stéphane Droupy ([email protected]) Vincent Molinié ([email protected]) Annick Vieillefond ([email protected]) Puay Hoon Tan ([email protected]) Stéphane Richard ([email protected]) Bin Tean Teh ([email protected])
منابع مشابه
Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes.
PURPOSE To compare gene expression profiles of chromophobe renal cell carcinoma (RCC) and benign oncocytoma, aiming at identifying differentially expressed genes. EXPERIMENTAL DESIGN Nine cases each of chromophobe RCC and oncocytoma were analyzed by oligonucleotide microarray. Candidate genes that showed consistent differential expression were validated by reverse transcription-PCR using 25 f...
متن کاملImmunohistochemical analysis of chromophobe renal cell carcinoma, renal oncocytoma, and clear cell carcinoma: an optimal and practical panel for differential diagnosis.
CONTEXT The separation of chromophobe renal cell carcinoma, oncocytoma, and clear cell renal cell carcinoma using light microscopy remains problematic in some cases. OBJECTIVE To determine a practical immunohistochemical panel for the differential diagnosis of chromophobe carcinoma. DESIGN Vimentin, glutathione S-transferase alpha (GST-alpha), CD10, CD117, cytokeratin (CK) 7, and epithelial...
متن کاملDiagnostic Utility of Caveolin-1 and MOC-31 in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma
PURPOSE Renal tumors consist of heterogeneous groups that frequently show complex and overlapping morphology, thus making it difficult to make a correct diagnosis. One of the most problematic differential diagnoses is to distinguish chromophobe renal cell carcinoma (RCC) from oncocytoma. These should be distinguished by differences in their behavior and clinical outcome. Our study was performed...
متن کاملS100 Expression in Oncocytoma and Chromophobe Renal Cell Carcinoma: An Immunohistochemical Study
Oncocytoma and chromophobe renal cell carcinoma may show a certain degree of histological overlap. The problem of differentiating both types is expected to increase because of the more frequent use of needle biopsies to diagnose small renal masses. In this study. The expression and the possible diagnostic utility of S 100 was evaluated in both oncocytoma and chromophobe renal cell carcinoma, us...
متن کاملOverexpression of KIT (CD117) in chromophobe renal cell carcinoma and renal oncocytoma.
KIT expression has not been studied substantially in renal tumors. We analyzed the immunohistochemical expression for KIT in 256 conventional renal cell carcinomas (RCCs), 29 chromophobe RCCs, 25 papillary RCCs, 6 collecting duct RCCs, 6 unclassified RCCs, 7 renal oncocytomas, 20 urothelial carcinomas, 7 nephroblastomas, and 23 angiomyolipomas. We found that 24 chromophobe RCCs (83%) and 5 rena...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2010